ASSESSMENT OF THE INFLUENCE OF PHARMACEUTICAL SUBSTANCES ON WATER BODIES AND CALCULATION OF THEIR CONCENTRATIONS ON THE EXAMPLE OF DICLOFENAC

Abstract

The entrance of pharmaceutical substances (PhS) into water bodies and their negative impact on the environment, including living organisms, has been proven by many research. The methods for identification these substances are very complicated and analytical equipment costs hundreds of thousands of hryvnias. Therefore, the development of a method for calculating PhS concentrations in surface and sewage waters as one of the tools for ecological monitoring is an extremely relevant task. Polluted sewage by PhS in a big city were calculated by three types: the first - as a result of treating patients in a hospital (hospital); the second - in treating diseases, hospitalized patients who are assigned to certain outpatient departments and take drugs for a certain period of time (outpatient) and the thirdly - patients who are treated independently (at home). A comparative analysis of the calculated and measured concentrations of diclofenac in natural and wastewaters showed a very good conformity.