Research of methods of inactivation of the antibiotic cyprofloxacin in order to prevent environmental pollution and protect human health

Abstract

Today the environmental problem of modern society is the rapid contamination of water resources around the world for pharmaceutical products, including antibiotics. According to the University of York (UK), contamination with antibiotics had covered two-thirds of the waterways of the planet. It was established experimentally that 90 % of antibiotics are applied into the surrounding environment: soil and water. Residues of medical drugs fall into rivers via human waste and animals and through the treatment plant, including pharmaceutical companies. On the other hand, under the influence of antibiotics can significantly change the biocenosis of water bodies. And bacteria gradually become immune to the effects of antibiotics. Therefore, the Ukrainian research Institute of ecological problems in cooperation with the National scientific center Kharkiv Institute of physics and technology experimental studies aimed at inactivation of bactericidal properties of antibiotic solution during processing ozone-air mixture. The study assessed the effectiveness of inactivation of antibiotic ciprofloxacin hydrochloride by methods related to deep oxidation AOPs technologies (Advanced Oxidation Processes) on the basis of combinations of ozonation, UV irradiation, treatment with hydrogen peroxide. Shown the prospects of using ozonation and O3/UV and O3/UV/H2O2 to reduce the toxic effect of the antibiotic residues of ciprofloxacin relative to the test object E. coli in the aquatic environment. Found that ozonation of activated sludge treated with ciprofloxacin, reduces the toxic effect of the antibiotic and promotes the enzymatic activity of the biocenosis of activated sludge